Pregnancy: There are no data from the use of anastrozole in pregnant women. Studies in animals have shown reproductive toxicity (see PHARMACOLOGY: Toxicology: Preclinical safety data under Actions). Anastrozole is contraindicated during pregnancy (see Contraindications).
Breast-feeding: There are no data on the use of anastrozole during lactation. Anastrozole is contraindicated during breast-feeding (see Contraindications).
Fertility: The effects of anastrozole on fertility in humans have not been studied. Studies in animals have shown reproductive toxicity (see PHARMACOLOGY: Toxicology: Preclinical safety data under Actions).